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1

Rheumatoid arthritis

Smolen, Josef S., Aletaha, Daniel, Barton, Anne, Burmester, Gerd R., Emery, Paul, Firestein, Gary S., Kavanaugh, Arthur, McInnes, Iain B., Solomon, Daniel H., Strand, Vibeke, Yamamoto, Kazuhiko

Journal:

Nature Reviews Disease Primers

Year:

2018

Language:

english

File:

PDF, 8.90 MB

english, 2018

2

Cytokines in the pathogenesis of rheumatoid arthritis

McInnes, Iain B., Schett, Georg

Journal:

Nature Reviews Immunology

Year:

2007

Language:

english

File:

PDF, 666 KB

english, 2007

3

Rheumatoid arthritis and depression: an inflammatory perspective

Nerurkar, Louis, Siebert, Stefan, McInnes, Iain B, Cavanagh, Jonathan

Journal:

The Lancet Psychiatry

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

4

Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis

Gracey, Eric, Burssens, Arne, CambrÃ©, Isabelle, Schett, Georg, Lories, Rik, McInnes, Iain B., Asahara, Hiroshi, Elewaut, Dirk

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2020

Language:

english

File:

PDF, 2.46 MB

english, 2020

5

The Pathogenesis of Rheumatoid Arthritis

McInnes, Iain B., Schett, Georg

Journal:

Boston Medical and Surgical Journal

Year:

2011

Language:

english

File:

PDF, 2.43 MB

english, 2011

6

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention*

O'Shea, John J., Schwartz, Daniella M., Villarino, Alejandro V., Gadina, Massimo, McInnes, Iain B., Laurence, Arian

Journal:

Annual Review of Medicine

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

7

Rheumatoid arthritis

Smolen, Josef S, Aletaha, Daniel, McInnes, Iain B

Journal:

Year:

2016

Language:

english

File:

PDF, 3.31 MB

english, 2016

8

Looking through the 'window of opportunity': is there a new paradigm of podiatry care on the horizon inearlyrheumatoid arthritis?

James Woodburn, Kym Hennessy, Martijn PM Steultjens, Iain B McInnes, Deborah E Turner

Journal:

Journal of Foot and Ankle Research

Year:

2010

Language:

english

File:

PDF, 632 KB

english, 2010

9

Europe rules on harm from fluoroquinolone antibiotics

Millar, Neal L., Siebert, Stefan, McInnes, Iain B.

Journal:

Year:

2019

Language:

english

File:

PDF, 66 KB

english, 2019

10

Pharmacological treatment of psoriatic arthritis: a systematic literature research for the 2019 update of the EULAR recommendations for the management of psoriatic arthritis

Kerschbaumer, Andreas, Smolen, Josef S, Dougados, Maxime, de Wit, Maarten, Primdahl, Jette, McInnes, Iain, van der Heijde, DÃ©sirÃ©e, Baraliakos, Xenofon, Falzon, Louise, Gossec, Laure

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 623 KB

2020

11

A reliability study of biomechanical foot function in psoriatic arthritis based on a novel multi-segmented foot model

Elaine Hyslop, James Woodburn, Iain B. McInnes, Ruth Semple, Lisa Newcombe, Gordon Hendry, Danny Rafferty, Sophie De Mits, Deborah E. Turner

Journal:

Year:

2010

Language:

english

File:

PDF, 556 KB

english, 2010

12

Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer?

Anthony F Lever, David J Hole, Charles R Gillis, Iain R McCallum, Gordon T McInnes, Pauline L MacKinnon, Peter A Meredith, Lilian S Murray, John L Reid, James WK Robertson

Journal:

Year:

1998

Language:

english

File:

PDF, 96 KB

english, 1998

13

Interleukin-21 – A biomarker of importance in predicting myocardial function following acute infarction?

Robin A.P. Weir, Ashley M. Miller, Colin J. Petrie, Suzanne Clements, Tracey Steedman, Henry J. Dargie, Iain B. Squire, Leong L. Ng, Iain B. McInnes, John J.V. McMurray

Journal:

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

14

Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial

McInnes, Iain B, Kavanaugh, Arthur, Gottlieb, Alice B, Puig, Lluís, Rahman, Proton, Ritchlin, Christopher, Brodmerkel, Carrie, Li, Shu, Wang, Yuhua, Mendelsohn, Alan M, Doyle, Mittie K

Journal:

Year:

2013

Language:

english

File:

PDF, 355 KB

english, 2013

15

Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial

McInnes, Iain B, Mease, Philip J, Kirkham, Bruce, Kavanaugh, Arthur, Ritchlin, Christopher T, Rahman, Proton, van der Heijde, Désirée, Landewé, Robert, Conaghan, Philip G, Gottlieb, Alice B, Richards,

Journal:

Year:

2015

Language:

english

File:

PDF, 383 KB

english, 2015

16

Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study

Baraliakos, Xenofon, Borah, Babul, Braun, Juergen, Baeten, Dominique, Laurent, Didier, Sieper, Joachim, Emery, Paul, McInnes, Iain B, van Laar, Jacob M, Wordsworth, Paul, Wollenhaupt, Juergen, Kellner

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 374 KB

english, 2015

17

Therapeutic Targeting of IL-17 and IL-23 Cytokines in Immune-Mediated Diseases

Fragoulis, George E., Siebert, Stefan, McInnes, Iain B.

Journal:

Annual Review of Medicine

Year:

2016

Language:

english

File:

PDF, 823 KB

english, 2016

18

Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid arthritis

Gabay, Cem, McInnes, Iain B, Kavanaugh, Arthur, Tuckwell, Katie, Klearman, Micki, Pulley, Jennifer, Sattar, Naveed

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 428 KB

english, 2015

19

Pathogenetic insights from the treatment of rheumatoid arthritis

McInnes, Iain B, Schett, Georg

Journal:

Year:

2017

Language:

english

File:

PDF, 337 KB

english, 2017

20

Clinical applications of machine learning algorithms: beyond the black box

Watson, David S, Krutzinna, Jenny, Bruce, Ian N, Griffiths, Christopher EM, McInnes, Iain B, Barnes, Michael R, Floridi, Luciano

Journal:

Year:

2019

File:

PDF, 1.04 MB

2019

21

Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study

Glatt, Sophie, Taylor, Peter C, McInnes, Iain B, Schett, Georg, Landewé, Robert, Baeten, Dominique, Ionescu, Lucian, Strimenopoulou, Foteini, Watling, Mark I L, Shaw, Stevan

Journal:

Annals of the Rheumatic Diseases

Year:

2019

Language:

english

File:

PDF, 1.43 MB

english, 2019

22

Europe rules on harm from fluoroquinolone antibiotics

Millar, Neal L., Siebert, Stefan, McInnes, Iain B.

Journal:

Year:

2019

File:

PDF, 66 KB

2019

23

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update

Smolen, Josef S, LandewÃ©, Robert B M, Bijlsma, Johannes W J, Burmester, Gerd R, Dougados, Maxime, Kerschbaumer, Andreas, McInnes, Iain B, Sepriano, Alexandre, van Vollenhoven, Ronald F, de Wit, Maart

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 1.35 MB

2020

24

Brodalumab in psoriatic arthritis: results from the randomised phase III AMVISION-1 and AMVISION-2 trials

Mease, Philip J, Helliwell, Philip S, Hjuler, Kasper Fjellhaugen, Raymond, Kyle, McInnes, Iain

Journal:

Annals of the Rheumatic Diseases

Year:

2020

File:

PDF, 1.67 MB

2020

25

IL-18 induces the differentiation of Th1 or Th2 cells depending upon cytokine milieu and genetic background

Damo Xu, Vladimir Trajkovic, David Hunter, Bernard P. Leung, Kerstin Schulz, J. Alastair Gracie, Iain B. McInnes, Foo Y. Liew

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

26

Interleukin-18: A novel cytokine in inflammatory rheumatic disease

Iain B. McInnes, J. Alastair Gracie, Foo Y. Liew

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 52 KB

english, 2001

27

Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis

Elli Kruithof, Leen De Rycke, Bernard Vandooren, Filip De Keyser, Oliver FitzGerald, Iain McInnes, Paul P. Tak, Barry Bresnihan, Eric M. Veys, Dominique Baeten, OMERACT Special Interest Group on Synov

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 290 KB

english, 2006

28

Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium: Ex vivo studies using a novel proteinase-activated receptor 2 antagonist

Elizabeth B. Kelso, William R. Ferrell, John C. Lockhart, Iona Elias-Jones, Todd Hembrough, Lynette Dunning, J. Alastair Gracie, Iain B. McInnes

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 221 KB

english, 2007

29

Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: A double-blind, placebo-controlled study

Naveed Sattar, Philippa Crompton, Lynne Cherry, David Kane, Gordon Lowe, Iain B. McInnes

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 110 KB

english, 2007

30

CXCR2-specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen-induced arthritis

Renata Grespan, Sandra Y. Fukada, Henrique P. Lemos, Silvio M. Vieira, Marcelo H. Napimoga, Mauro M. Teixeira, Alasdair R. Fraser, Foo Y. Liew, Iain B. McInnes, Fernando Q. Cunha

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

31

Golimumab, a new human tumor necrosis factor α antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty-four–week efficacy and safety results of a randomized, placebo-controlled study

Arthur Kavanaugh, Iain McInnes, Philip Mease, Gerald G. Krueger, Dafna Gladman, Juan Gomez-Reino, Kim Papp, Julie Zrubek, Surekha Mudivarthy, Michael Mack, Sudha Visvanathan, Anna Beutler

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 124 KB

english, 2009

32

Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis

Darren L. Asquith, Ashley M. Miller, Axel J. Hueber, Heather J. McKinnon, Naveed Sattar, Gerry J. Graham, Iain B. McInnes

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

33

Apolipoprotein E–deficient mice are resistant to the development of collagen-induced arthritis

Darren L. Asquith, Ashley M. Miller, Axel J. Hueber, Foo Y. Liew, Naveed Sattar, Iain B. McInnes

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 196 KB

english, 2010

34

Erratum: Golimumab, a new human tumor necrosis factor α antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty-four–week efficacy and safety results of a randomized, placebo-controlled study

Arthur Kavanaugh, Iain McInnes, Philip Mease, Gerald G. Krueger, Dafna Gladman, Juan Gomez-Reino, Kim Papp, Julie Zrubek, Surekha Mudivarthy, Michael Mack, Sudha Visvanathan, Anna Beutler

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 31 KB

english, 2010

35

Characterization of the anticollagen antibody response in a new model of chronic polyarthritis

Paola Conigliaro, Robert A. Benson, Agapitos Patakas, Sharon M. Kelly, Guido Valesini, Rikard Holmdahl, James M. Brewer, Iain B. McInnes, Paul Garside

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

36

Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis

Mark H. Wenink, Kim C. M. Santegoets, John Butcher, Lenny van Bon, Femke G. M. Lamers-Karnebeek, Wim B. van den Berg, Piet L. C. M. van Riel, Iain B. McInnes, Timothy R. D. J. Radstake

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 314 KB

english, 2011

37

Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice

Lindsay M. MacLellan, Jennifer Montgomery, Fujimi Sugiyama, Susan M. Kitson, Katja Thümmler, Gregg J. Silverman, Stephen A. Beers, Robert J. B. Nibbs, Iain B. McInnes, Carl S. Goodyear

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 836 KB

english, 2011

38

Prior elevation of IL-18 promotes rapid early IFN-γ production during staphylococcal infection

Shauna Culshaw, Bernard P. Leung, J. Alastair Gracie, Carol C. Campbell, Duncan Thomson, Curtis Gemmell, Foo Y. Liew, Iain B. McInnes

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

39

Expression and alternative processing of IL-18 inhuman neutrophils

Susan E. Robertson, John D. Young, Susan Kitson, Andrew Pitt, Jamie Evans, Jurgen Roes, Denise Karaoglu, Ling Santora, Tariq Ghayur, Foo Y. Liew, J. Alastair Gracie, Iain B. McInnes

Journal:

European Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

40

IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production

Waldiceu A. Verri Jr., Thiago M. Cunha, Sérgio H. Ferreira, Xiaoqing Wei, Bernard P. Leung, Alasdair Fraser, Iain B. McInnes, Foo Y. Liew, Fernando Q. Cunha

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 266 KB

english, 2007

41

IL-33 is a chemoattractant for human Th2 cells

Mousa Komai-Koma, Damo Xu, Yubin Li, Andrew N. J. McKenzie, Iain B. McInnes, Foo Y. Liew

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 342 KB

english, 2007

42

IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

Wanda Niedbala, Xiao-qing Wei, Beilei Cai, Axel J Hueber, Bernard P. Leung, Iain B. McInnes, Foo Y. Liew

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 376 KB

english, 2007

43

Correction: IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells

Wanda Niedbala, Xiao-qing Wei, Beilei Cai, Axel J Hueber, Bernard P. Leung, Iain B. McInnes, Foo Y. Liew

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 36 KB

english, 2007

44

Animal models of rheumatoid arthritis

Darren L. Asquith, Ashley M. Miller, Iain B. McInnes, Foo Y. Liew

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

45

IL-33 induces skin inflammation with mast cell and neutrophil activation

Axel J. Hueber, Jose C. Alves-Filho, Darren L. Asquith, Chesney Michels, Neal L. Millar, James H. Reilly, Gerry J. Graham, Foo Y. Liew, Ashley M. Miller, Iain B. McInnes

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 498 KB

english, 2011

46

Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design

George Kontopidis, Campbell McInnes, Sravan R. Pandalaneni, Iain McNae, Darren Gibson, Mokdad Mezna, Mark Thomas, Gavin Wood, Shudong Wang, Malcolm D. Walkinshaw, Peter M. Fischer

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 350 KB

english, 2006

47

ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential

William Harnett, Iain B McInnes, Margaret M Harnett

Journal:

Immunology Letters

Year:

2004

Language:

english

File:

PDF, 118 KB

english, 2004

48

Immune regulation in psoriasis and psoriatic arthritis—Recent developments

Axel J. Hueber, Iain B. McInnes

Journal:

Immunology Letters

Year:

2007

Language:

english

File:

PDF, 121 KB

english, 2007

49

Murine neutrophils present Class II restricted antigen

Shauna Culshaw, Owain R. Millington, James M. Brewer, Iain B. McInnes

Journal:

Immunology Letters

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

50

Interleukin 18: a pleiotropic participant in chronic inflammation

Iain B. McInnes, J.Alastair Gracie, Bernard P. Leung, Xiao-Qing Wei, Foo Y. Liew

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000